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Choose Mail > Preferences, then click Accounts.
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Select the required account.
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Click Account Information, then review the server being used for outgoing messages; this should be exchange.mthservers.com.
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If None is selected, click the Outgoing Mail Server pop-up menu, and select exchange.mthservers.com from the drop down list.
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If you don't see exchange.mthservers.com on the drop down list click Edit SMTP Server List and use the help (?) icon in the bottom left to guide you through what information you need to enter. The Outgoing server (SMTP) is exchange.mthservers.com: port 465 for SSL, port 26/587 for TLS.
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Test your changes by sending yourself a message.